Powering the future of gene editing development

The next generation of genome-wide on- and off-target analysis in your own hands

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The new standard for rapid detection of gene editing-induced breaks

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Scales from

discovery to IND

Support guide screening, optimization, and downstream characterization

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Works across cell

types & editors

Use one approach across diverse cell models and nuclease systems

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Reproducible

standardized data

Generate decision-ready outputs you can trust across programs

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Single

unified workflow

Replace fragmented assays with one consistent approach

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No outsourcing.
No black-box services.
Full control of your data.

The BreakMap platform powered by INDUCE-seq® delivers fast, unbiased on- and off-target analysis entirely in-house, replacing fragmented legacy workflows with a single standardized assay.

Integrated bioinformatics converts complex genome-wide sequencing data into clear, ranked outputs, for confident decision-making.

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Discover bioinformatics

From edited cells to genome-wide insights in a single workflow

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Cell editing &
immobilization

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DNA break labeling
& library prep

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Sequencing

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Data analysis

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Reporting

Reduce program risk with confident genome-wide on- and off-target insights

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Identify the best-performing guides in days

Avoid late-stage failures caused by hidden off-targets

Build robust regulatory packages with empirical data

Translate sequencing data into clear, ranked on- and off-target insights

Simplify workflows and reduce dependence on bespoke assays

Identify and characterize new editing tools

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a scientist

Explore the technology

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Latest news and updates

Newsroom
ÃÛÌÒ´«Ã½ Rebrands to Reflect Strategic Evolution as Demand Grows for Unbiased Genome-wide Off-target Analysis
ÃÛÌÒ´«Ã½ Rebrands to Reflect Strategic Evolution as Demand Grows for Unbiased Genome-wide Off-target Analysis

Alongside rebranding, we have redesigned our website so researchers can easily access a comprehensive resource library and gain a clear understanding of how our INDUCE-seq platform can be applied across gene editing workflows to maximize value in development pipelines.

ÃÛÌÒ´«Ã½ Announces New Leadership to Drive Commercialization of INDUCE-seq® Platform for Gene Editing On- and Off-target Characterization
ÃÛÌÒ´«Ã½ Announces New Leadership to Drive Commercialization of INDUCE-seq® Platform for Gene Editing On- and Off-target Characterization

To drive the company’s commercial expansion, Terry Pizzie has been appointed as CEO, bringing extensive experience from leading and scaling global life science businesses.

ÃÛÌÒ´«Ã½ Renews Commitment to NIST Genome Editing Consortium, Bolstering Efforts to Standardize Gene Editing Safety
ÃÛÌÒ´«Ã½ Renews Commitment to NIST Genome Editing Consortium, Bolstering Efforts to Standardize Gene Editing Safety

Broken String’s participation in the NIST Genome Editing Consortium is part of the company’s efforts to shape industry-wide safety standards for emerging genome editing technologies, including CRISPR, base editing, and prime editing.

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